Study suggests antiretroviral therapy does not restore disease immunity

(SUNY Downstate Health Science University) A study led by researchers from SUNY Downstate Health Sciences University and Oregon Health & Science University, published in the Journal of Infectious Diseases, showed that, despite successful antiretroviral therapy (ART), antigen specific memory to vaccinations that occurred before HIV infection did not recover, even after immune reconstitution. Additionally, a previously unrealized decline in preexisting antibody response was also observed.